The U.S. Coast Guard has projected that the crew of five men aboard a missing submersible vessel exploring the Titanic wreckage will run out of oxygen by 7 a.m. EDT on Thursday. The submersible, named Titan, disappeared in the waters of Newfoundland on Sunday during an OceanGate Expeditions mission. It was equipped with a 96-hour supply of emergency oxygen, meaning the crew will exhaust their air supply by Thursday morning. The Coast Guard spokesperson stated that any further estimates are too uncertain to confirm. The search efforts, led by the Coast Guard, Navy, Canadian Coast Guard, and OceanGate Expeditions, are focused on search and rescue, not recovery. The search operation is complex, covering an area twice the size of Connecticut on the surface and at a depth of about 2.5 miles underwater. The rescue experts are facing challenges due to changing weather conditions and expanding search areas. International experts and Canadian partners are providing assistance, and additional assets are en route to the location. The joint search efforts have deployed air, surface, and subsurface assets.